SysCLFT (Systems tool for Cleft Lip/palate gene discovery)
Using SysCLFT for prioritization of genes within a mapped interval for orofacial clefts
SysCLFT tracks allow the visualization of genes in context of their enrichment of expression in CF tissue. After opening the browser for the human genome assembly window, the user can type in the interval of interest and the entire genome track is loaded. This representation allows immediate visual detection of the best candidates in a given genomic interval, and allows one to zoom in or out to visualize the presence of promising candidates within a particular region or proximal to it.
To test a genomic region of interest for orofacial cleft candidate genes, open a specific genome assembly on the UCSC Genome Browser with SysCLFT tracks by clicking on the following links:
- Human hg19 All
- Human hg19 Mandible
- Human hg19 Maxilla
- Human hg19 Frontonasal
- Human hg19 Palate
- Mouse mm9 All
- Mouse mm9 Mandible
- Mouse mm9 Maxilla
- Mouse mm9 Frontonasal
- Mouse mm9 Palate